What Is the Next Letter? 12 Fun Letter Sequence Puzzles
The following is our collection of some of the most fun and satisfying letter-sequence puzzles, each designed to exercise your brain in an enjoyable and informative way. Every puzzle is built around a hidden pattern that will keep you thinking, guessing, and smiling as everything finally clicks into place.
Puzzle #1
What letter comes next in this sequence? A, H, I, M, O, T, _

Hint
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HINT: Look at the structure of each letter.
Answer & Explanation
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Answer: The next letter in the sequence is U.
Explanation:
The given sequence consists of vertically symmetric letters: A, H, I, M, O, T. Vertically symmetric letters are those that, when divided vertically down the center, are mirror images on both sides. In uppercase, these letters include:
- A
- H
- I
- M
- O
- T
- U
- V
- W
- X
- Y
These letters remain unchanged when reflected across a vertical axis.
As aforementioned, vertically symmetric letters remain unchanged when split down the middle. After “T,” the next vertically symmetric letter is “U,” which fits the pattern.
Puzzle #2
Can you figure out the letter that comes next?
U R R R A U ?

Answer & Explanation
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Answer: U
Explanation:
This sequence takes the middle letter of each month’s name. If the month’s name has an even number of letters, the first of the two middle letters is selected. Here’s how the sequence breaks down:
- U from “JanUary”
- R from “FebRuary”
- R from “MaRch”
- R from “ApRil”
- A from “MAy”
- U from “JUne”
Following this pattern, the next month is July, and the middle letter of “July” is U. Therefore, the next letter is U.
Puzzle # 3
What letter comes next in the sequence?

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Answer: N
Explanation: Each letter is the first letter of the English word for successive prime numbers:
2 → Two → T
3 → Three → T
5 → Five → F
7 → Seven → S
11 → Eleven → E
13 → Thirteen → T
17 → Seventeen → S
19 → Nineteen → N
23 → Twenty-three → T ← next
So the next letter is N.
Puzzle #4
What letter comes next in the sequence?

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Answer: S
Explanation: S
The second letters go down one step each time — V, U, T, so next is S.
Another Valid Route:
Each pair sums to 27 (A=1…Z=26). E(5)+V(22)=27, F(6)+U(21)=27, G(7)+T(20)=27, so H(8) pairs with 19 → S.
Puzzle #5
Can you figure out the letter that comes next?

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Answer: V
Explanation: The letters are the first initials of the U.S. Presidents in order:
- Washington → W
- Adams → A
- Jefferson → J
- Madison → M
- Monroe → M
- John Quincy Adams → A
- Jackson → J
- Van Buren → V ← next
So the next letter is V (for Van Buren).
Puzzle #6
Can you figure out the letter that comes next?

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Answer: N
Explanation: The letters are the first letters of the proverb “A stitch in time saves nine.”
A (A) → S (Stitch) → I (In) → T (Time) → S (Saves) → N (Nine).
Puzzle # 7
What letter comes next in the sequence?

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Answer: H
The pattern follows the position of each word’s order number within its spelling. In other words, you take the 1st letter of “FIRST,” the 2nd letter of “SECOND,” the 3rd letter of “THIRD,” the 4th letter of “FOURTH,” and the 5th letter of “FIFTH.”
So it works like this:
- FIRST → F
- SECOND → E
- THIRD → I
- FOURTH → R
Following the same rule:
5. FIFTH → H
Puzzle #8
What is the next letter?

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Answer: H
Explanation:
The sequence follows two interwoven patterns happening at the same time.
If we split the letters into two groups, we can clearly see the structure:
First group (end of the alphabet):
Y, W, U — these move backwards through the alphabet, skipping one letter each time (Y → W → U).
Second group (start of the alphabet):
B, D, F — these move forward through the alphabet, also skipping one letter each time (B → D → F).
So the pattern is made of two alternating sequences:
- One going backward from the end of the alphabet
- One going forward from the beginning
Continuing both patterns together, the next missing letter completes the forward progression from the second sequence, leading to:
H
Puzzle #9
Can you figure out the letter that comes next?

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Answer: C
Explanation:
Read the QWERTY keyboard column by column, top → bottom, left → right:
- 1st column: Q → A → Z
- 2nd column: W → S → X
- 3rd column: E → D → C ← next
So after E, D comes C.
Puzzle #10
Can you figure out the letter that comes next?

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Answer: S
Explanation:
These are the first letters of the major ranks in biological classification, from broadest to most specific:
- Domain
- Kingdom
- Phylum
- Class
- Order
- Family
- Genus
- Species
S (Species) is the final standard main rank, so the sequence has reached its end.
Puzzle #11
My quirky Uncle Philippe always has a tricky puzzle up his sleeve.
The last time I visited, he waved a notepad in front of me and said, “Voilà! I’ve got another sequence for you!” He showed me this string of letters:
UI, AI, EEI, EUI, EEI, AEI, __
“Now, what comes next?” he asked with a mischievous grin, leaving me to ponder the pattern.
Can you help me figure out what comes next in the sequence?

Answer & Explanation
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Answer: The next combination in the sequence is IAE.
Explanation:
This sequence is formed by extracting the vowels from the French names of the days of the week. Here’s the breakdown:
- LUNDI (Monday) gives us UI.
- MARDI (Tuesday) gives us AI.
- MERCREDI (Wednesday) gives us EEI.
- JEUDI (Thursday) gives us EUI.
- VENDREDI (Friday) gives us EEI (which repeats).
- SAMEDI (Saturday) gives us AEI.
Following this pattern, the next day is DIMANCHE (Sunday). The vowels from “DIMANCHE” are I, A, E.
Thus, the correct continuation of the sequence is IAE.
Voilà! was more than just flair — it was a clue that the answer involved the French language.
Puzzle# 12
What is the next letter?

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This last one is for you to figure out. If stuck, let us know
